• Marc Leone


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    Email —  ******@***ap-hm.fr
    Service d'Anesthésie et de Réanimation Aix-Marseille University; Assistance Publique Hôpitaux de Marseille

Featured in HealthManagement.org

  • Carbon Footprint in ICU: A New Meaningful Outcome in Research Trials

    • 26/05/2023

    Reducing the carbon footprint in healthcare is a requirement for guaranteeing the best future for humanity. Here we suggest that the carbon footprint be assessed as a potential endpoint for future trials in critical care.   Environmental Impact in Critical Care The climate crisis is a threat to global health. The temperature of the atmosphere has been rising exponentially since the indust

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  • Does Antimicrobial Resistance Affect Clinical Outcomes in the ICU?

    • 14/10/2022

    An overview of antimicrobial resistance and its impact on clinical outcomes in the ICU.  Antimicrobial resistance (AMR) has been defined as a major threat to healthcare and to humanity by the World Health Organization (WHO 2015). The level of evidence for the association between AMR and hospital deaths, hospital length of stay and healthcare-associated costs is growing. Cassini et al. (2019)...

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  • The Alphabet Book of Sepsis

    • 16/03/2022

    In this article, the author provides the alphabet review of sepsis and septic shock based on personal clinical experience and choice. Sepsis and septic shock have been defined in 2016 (Singer et al. 2016) and the management of patients is framed by the Surviving Sepsis Campaign guidelines with its renewed version in 2021 (Evans et al. 2021). Using PubMed, around 15,000 hits respond to the...

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  • Sex in the Intensive Care

    • 24/08/2021

    Change content default valueSex interplays with the development of several diseases and syndromes, impacting differently the need for intensive care unit admission between men and women. All in all, men are more prone to develop critical illness than women, which explains their over-representation in the intensive care unit. On the other hand, treatments differ between men and women with more aggressive...

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  • Oxygen: Too Much is Bad

    • 24/06/2021

    Supplemental oxygen administration is a routine treatment administered to a wide majority of critically ill patients. Nevertheless, evidence suggest that exposure to hyperoxia is associated with impaired outcomes. We discuss here the benefits and harms of supplemental oxygen administration in the intensive care unit. Introduction In the intensive care unit (ICU), supplemental oxygen administration

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  • Future Strategies in Sedation and Analgesia

    • 15/01/2020

    From massive sedation in the past, through current patient-centred sedation protocols, the future may further improve sedation in the ICU. Introduction The concepts for an optimal sedation in the intensive care unit (ICU) should include: Definition of the optimal depth of sedation; The need for agents with on/off effects; The need for agents with dedicated effects on hypnosis,...

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  • Good past—better future?

    • 24/01/2019

    From massive sedation in the past, through current sedation practice relying on cooperation between patients and care providers, the future may further improve sedation in the ICU.   The concepts for good sedation include defining the range of sedation, the need for agents with rapid response that can be easily and rapidly varied in restless and confused patients, various modes of ventilatio

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